Smallpox and chickenpox

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1

What is the causative organism for smallpox

variola virus

2

What family of viruses does smallpox belong

poxvirus

3

what is the genome of smallpox

dna double stranged

4

Does this virus always have an envelope

no

5

What is the shape of the variola (smallpox) virus?

brick shape

6

What is the organization known as WHO

World Health Organization

7

How was smallpox eliminated as a naturally occurring infection?

successful vaccine program

8

When was the last naturally occurring case of smallpox reported in the world

1977 in Africa

9

What 2 labs are authorized to handle the smallpox virus

US, CDC and Russia

10

What are some possible modes of transmission for smallpox

Air droplets person-to-person, coughing, breathing
Contact with skin sores, contaminated clothing or bedding

11

Is smallpox contagious

yes, highly

12

Is smallpox always fatal

no

13

What are the clinical symptoms for smallpox

high fever, fatigue, headache, backache
macular rash or pox, pink spots begin in mouth

14

What is the duration of a typical smallpox case until recovery

25-30 days?

15

What is the difference between the macular, vesicular and pustular rash?

-Macular is pink spots
-vesicular is fluid filled small red bumps with dip in center
-pustular is pus filled hard round bumps

16

Is there a vaccine for smallpox

yes

17

What is the difference between variolation and vaccination

vaccination is an injection
variolation is a thread saturated with fluid from smallpox lesions introduced into scratch of nonimmune person

18

Who was lady montagu and what is her significance in history

wife of british ambassador to turkey who introduced variolation to england

19

Is cowpox in the same family of viruses as smallpox

yes

20

Who was Edward Jenner and what was his contribution to the smallpox vaccine

He improved small pox immunization by discovering cowpox exposure immunized against smallpox creating vacca(cow) vaccine

21

What is the component of the vaccine for smallpox

vacinia virus which is live material

22

What is an attenuated vaccine

live material

23

How long does immunity last after smallpox vaccine

3-5yrs and no more than 10yrs

24

What is a bifurcated needle?

needle with 2 sharp ends that holds one drop of virus in between

25

Are there side effects from the smallpox vaccine?
Is there any segment of the population that should not receive this vaccine because of high risk?

Yes, Encephalitis and progressive vaccinia, eczema vaccinatum, generalized vaccinia.
Yes there is a population that shouldn't receive vaccine: cancer pts, immune deficiency, skin conditions, pregnancy

26

Is anyone vaccinated for smallpox today?

scientists that handle smallpox or related virus
military personnel
select healthcare workers
select emergency personnel

27

Is there treatment for smallpox

No known

28

Is there immunity after recovery of a natural infection with smallpox

yes

29

What is the availability of smallpox virus to a terrorist

very low

30

What is a N95 respirator

It filters atleast 95% of particles and reduced exposure but doesn't illiminate it

31

What would be the danger of reintroducing smallpox in today's world

could be catastrophic

32

What is the causative organism for chickenpox

varicella

33

What family of viruses does chickenpox belong?

herpes virus

34

What is the genome of this virus

double stranded dna

35

Does chickenpox virus have an envelope?

yes

36

What is the shape of chickenpox virus

icosahedral

37

What are the clinical symptoms of chickenpox

fever and rash start at same time

38

Are chickens a reservoir for this virus

no

39

Is there a vaccine for chickenpox

yes

40

What disease results when chickenpox recurs

shingles

41

Which disease is typically more serious: smallpox or chickenpox

smallpox


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