What determines female baby?
Design or Default
Mesonephric duct degenerates and paramesopnephric duct develops
What is another name for the paramesonephric duct?
Mullerian duct hence the name Mullerian inhibitory Factor which inhibits the paramesonephric duct
what determines male baby?
1. SRY gene on Y chromosome Testis developing factor
2. Mullerian inhibitory Factor (MIF) (Sertoli cells)
3. Androgen (Leydig cells) development of Mesonephric ducts.
What does the Paramesonephric duct develop into?
Internal Female genitalia
Upper portion of the vagina
What is Mullerian agenesis (Mayer-Rokitansky-Kuster-Hauser syndrome?)
Primary amenorrhea with fully developed ovaries.
No Mullerian (Paramesonephric) structures
What is the another name for Mesonephric (Wolffian) duct?
Develops into the male internal structures minus PROSTATE (SEED)
What is the female remnant of the Paramesonephric duct?
What is the male remnant of the mesonephric duct?
What hormone is responsible for male external genitalia?
What hormone is responsible for male internal genitalia?
Lack of Sertoli cells or Mullerian inhibitory factor has what effect on male genitalia development?
both male and female INSIDE
What effect does 5-alpha-reductase def have one male genitalia development?
NO DHT = External problem
Ambiguous external until puberty which causes masculinization
What are the Mullerian duct anomalies?
Septate uterus - incomplete resorption of septum
Bicornuate uterus - incomlete fusion
Uterus didelphys double uterus, vagina, cervix