HIV

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1

Evolution Darwin Definition

Descent with modification

2

Evolution textbook Definition

Change in the genetic composition of a population through time, that is, across generations

3

AIDS stands for

A cquired I mmuno d eficiency S yndrome

4

Acquired

the disease is not hereditary but develops after birth from contact with a disease causing agent (HIV).

5

Immunodeficiency

– the disease is characterized by a weakening of the immune system.

6

Syndrome

refers to a group of symptoms that collectively indicate or characterize a disease. In the case of AIDS, this can include the development of co-infections and/or cancers, as well as a decrease in the number of certain cells in a person’s immune system.

7

What are the steps a Retrovirus takes

RNA → DNA → RNA → Protein

8

How HIV cause AIDs

destroys CD4 helper T cells, immune response impaired and kills people indirectly by weakening the immune system, allowing opportunistic infections.

9

Three ways Resistance to AZT occurs

(1) Mutation occurs in the active site of reverse transcriptase

(2) AZT no longer incorporated in new viral DNA. Normal T incorporated preferentially

(3) See the same mutation in different patients


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